发明名称 Catecholamine pharmaceutical compositions and methods
摘要 Pharmaceutical compositions and method using adrenergic compounds and complement compounds. Compositions are provided comprising: (c) a subefficacious amount of an adrenergic compound; and (d) a safe and effective amount of a complement to the adrenergic compound. Methods are also provided comprising the administration of: (c) a low dose of an adrenergic compound; and (d) a safe and effective amount of a complement to said adrenergic compound. Preferably, the adrenergic compound is a catecholamine. Complements include ascorbates, opioids, polycarboxylic acid chelaters, and mixtures thereof. Preferred complements include ascorbates, particularly ascorbic acid. Methods include the treatment of neurological disorders, hypotension, forward failure, backward failure, congestive heart failure, shock, hypertension, hemorrhage, disorders associated with anesthesia, chronic obstructive pulmonary disease, asthma, colic, Crohn's disease, anaphylaxis, interstitial cystitis, overactive bladder syndrome, premature labor, myethsenia gravis, and glaucoma.
申请公布号 US2003216413(A1) 申请公布日期 2003.11.20
申请号 US20030401421 申请日期 2003.03.28
申请人 ROOT-BERNSTEIN ROBERT S.;DILLON PATRICK F. 发明人 ROOT-BERNSTEIN ROBERT S.;DILLON PATRICK F.
分类号 A61K31/137;A61K31/195;A61K31/198;A61K31/375;A61K31/415;A61K31/485;A61K31/52;A61K31/522;A61K31/7004;A61K31/7076;A61K45/06;A61P1/04;A61P9/00;A61P9/02;A61P9/04;A61P9/12;A61P11/00;A61P11/06;A61P11/08;A61P13/10;A61P15/06;A61P21/00;A61P21/02;A61P21/04;A61P25/00;A61P25/02;A61P25/16;A61P25/18;A61P27/00;A61P27/02;A61P27/06;A61P27/16;A61P37/08;A61P43/00;(IPC1-7):A61K31/522 主分类号 A61K31/137
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