| 发明名称 |
Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method |
| 摘要 |
This invention discloses a novel method for immobilizing molecules to a support. Specifically, this invention discloses a method of immobilizing derivatized biomolecules, such as oligonucleotides, using cycloaddition reactions, such as the Diels-Alder reaction. Included in this invention are the novel immobilized biomolecules that can be prepared according to the method of this invention.
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| 申请公布号 |
US2003215801(A1) |
申请公布日期 |
2003.11.20 |
| 申请号 |
US20010845742 |
申请日期 |
2001.05.01 |
| 申请人 |
PIEKEN WOLFGANG;WOLTER ANDREAS;SEBESTA DAVID P.;LEUCK MICHAEL;LATHAM-TIMMONS HALLIE A.;PILON JOHN;HUSAR GREGORY M. |
发明人 |
PIEKEN WOLFGANG;WOLTER ANDREAS;SEBESTA DAVID P.;LEUCK MICHAEL;LATHAM-TIMMONS HALLIE A.;PILON JOHN;HUSAR GREGORY M. |
| 分类号 |
C07B61/00;C07C215/10;C07C271/16;C07D207/46;C07F7/18;C07F9/24;C07H21/00;(IPC1-7):C12Q1/68;G01N33/53;G01N33/542;B05D3/00 |
主分类号 |
C07B61/00 |
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