| 摘要 |
A topical formulation including a solvent, an occlusive agent, a surfactant system, an androstane steroid compound of formula (I) wherein R<1 >represents a fluoro-, chloro- or bromo-methyl group or a 2'-fluoroethyl group, R<2 >represents a group COR<6 >where R<6 >is a C1-3 alkyl group or OR<2 >and R<3 >together form a 16alpha, 17alpha-isopropylidenedioxy group; R<3 >represents a hydrogen atom, a methyl group (which may be in either the alpha- or beta-configuration) or a methylene group; R<4 >represents a hydrogen, chlorine or fluorine atom; R<5 >represents a hydrogen or fluorine atom and the symbol --- represents a single or double bond, and the balance being water.
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