发明名称 |
SYSTEM AND METHOD FOR TREATING CARDIAC ARRHYTHMIAS WITH FIBROBLAST CELLS |
摘要 |
A system (20) delivers fibroblasts to a region of cardiac tissue at a location associated with a cardiac arrhythmia in a patient to form a conduction block in the region. A cardiac delivery system (20) is coupled to a source the fibroblasts (15) and delivers the fibroblasts to the location to form a conduction block. Substantial cardiac ablation is thus avoided. A contact member (430) is shaped to correspond with a patterned region of tissue for delivering the fibroblasts along the pattern, such as linear, curvilinear, or circumferential patterns as required for treating particular arrhythmias. A pulmonary vein isolation assembly has an expandable or loop shaped member cooperating with a needle array that delivers the fibroblast cells into a circumferential region of tissue engaged by the expandable member where a pulmonary vein extends from an atrium. Methods include providing the fibroblast cells as autologous cells in an injectable preparation.
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申请公布号 |
WO03094855(A1) |
申请公布日期 |
2003.11.20 |
申请号 |
WO2003US14880 |
申请日期 |
2003.05.07 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;RHYTHM THERAPEUTICS CORPORATION;LEE, RANDALL, J.;MACIEJEWSKI, MARK |
发明人 |
LEE, RANDALL, J.;MACIEJEWSKI, MARK |
分类号 |
A61N1/05;A61B17/00;A61F2/84;A61K35/12;A61K35/36;A61M25/00;A61M25/10;A61M31/00;A61P9/06;C12N5/02;C12N5/077;(IPC1-7):A61K/ |
主分类号 |
A61N1/05 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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