发明名称 METHOD FOR PREPARING LIPOSOMES
摘要 FIELD: medicine, pharmacy. SUBSTANCE: invention relates to method for preparing liposomes. Method for preparing the reagent composition involves the following stages: (i) formation of empty liposomes; (ii) mixing liposomes prepared at stage (i) with sugar solution and reagent and (iii) drying mixture obtained at stage (ii). As a whole, composition comprises less 10% (weight/volume) of sucrose. Invention provides preparing small liposomes with high incapsulating activity. It can be especially useful in production of pharmaceutical preparations, allows reducing number of process stages and to obtain stable liposomes with highly effective incapsulating capacity. EFFECT: improved preparing method. 22 cl, 12 tbl, 6 dwg, 11 ex
申请公布号 RU2216315(C2) 申请公布日期 2003.11.20
申请号 RU20010101910 申请日期 1999.06.16
申请人 DZE SEKRETEHRI OF STEJT FOR DEFENS 发明人 GREGORIADIS GREGORI;ZADI BRAKHIM;DZHAJASEKERA PRAMUKKH NALAKA
分类号 A61K9/127;A61K47/26;(IPC1-7):A61K9/127 主分类号 A61K9/127
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