发明名称 Biaromatic compounds and pharmaceutical and cosmetic compositions comprising them
摘要 The invention concerns bi-aromatic compounds of formula (I) in which Ar represents (a), Z being O or S, R1 is CH3, -CH2-O-R6, -OR6 or -COR7; R2 is -OR8, -SR8 or a polyether radical if in the latter case R4 is C1-C20alkyl and is in ortho or meta position relative to X-Ar: R3 is alkyl or R2 and R3 together form a cycle optionally interrupted by O or S, R4 is aryl radical; R5 is H, halogen, C1-C20 alkly or -OR8; R6 is H, alkyl or -COR9; R7 is H, alkyl, -N(r')(r'') or -OR10; R8 is H, alkyl or -COR9; R9 is alkyl; R10 is H, C1-C20 alkyl, alkenyl, monohydroxyalkyl or polyhydroxyalyl, aryl or aralkyl or a sugar residue, r' and r'' are H, alkyl mono- or polyhydroxyalkyl, aryl, an amino acid or sugar residue or together form a heterocycle, X represents a radical of formula (d) or (e) in which R11 is H or -OR6; R12 is H or alkyl; or R11 and R12 form an oxo radical, and the salts, optical and geometrical isomers of the compounds of formula (I).
申请公布号 US2003216586(A1) 申请公布日期 2003.11.20
申请号 US20010984830 申请日期 2001.10.31
申请人 GALDERMA RESEARCH & DEVELOPMENT 发明人 BERNARDON JEAN-MICHEL;TROUILLE SIMON
分类号 A61K8/00;A61K8/14;A61K8/30;A61K8/31;A61K8/33;A61K8/35;A61K8/36;A61K8/368;A61K8/37;A61K8/39;A61K8/44;A61K8/46;A61K8/49;A61K8/60;A61K8/64;A61K31/192;A61K31/22;A61K31/35;A61K31/352;A61K31/382;A61P9/00;A61P9/10;A61P11/00;A61P17/00;A61P17/02;A61P17/06;A61P17/10;A61P17/14;A61P17/16;A61P19/02;A61P27/02;A61P29/00;A61P35/00;A61P37/08;A61Q5/00;A61Q5/02;A61Q19/00;A61Q19/02;A61Q19/10;C07C65/19;C07C65/28;C07C69/76;C07D213/79;C07D311/58;C07D335/06;C07D405/06;C07D409/06;(IPC1-7):C07D333/16;C07D333/18;C0737/40;C07D213/63 主分类号 A61K8/00
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