发明名称 |
Methods for using 22045, a human cyclic nucleotide phosphodiesterase |
摘要 |
The present invention relates to methods for using a human cyclic nucleotide phosphodiesterase belonging to the superfamily of mammalian phosphodiesterases. The invention also relates to methods for using polynucleotides encoding the phosphodiesterase. The invention relates to methods using the phosphodiesterase polypeptides and polynucleotides as a target for diagnosis and treatment in phosphodiesterase-mediated or -related disorders. The invention further relates to drug-screening methods using the phosphodiesterase polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the phosphodiesterase polypeptides and polynucleotides. The invention further relates to agonists and antagonists identifiefd by drug screening methods with the phosphodiesterase polypeptides and polynucleotides as a target.
|
申请公布号 |
US2003215898(A1) |
申请公布日期 |
2003.11.20 |
申请号 |
US20030458839 |
申请日期 |
2003.06.11 |
申请人 |
MILLENNIUM PHARMACEUTICALS, INC. |
发明人 |
KAPELLER-LIBERMANN ROSANA;HUNTER JOHN JOSEPH;WILLIAMSON MARK |
分类号 |
A01K67/027;A61K35/76;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P5/00;A61P9/04;A61P9/10;A61P35/00;C12N5/06;C12N5/10;C12N9/16;C12N15/09;C12N15/55;C12Q1/02;C12Q1/34;C12Q1/68;G01N33/15;G01N33/50;G01N33/53;G01N33/566;(IPC1-7):A61K31/00;C12Q1/44 |
主分类号 |
A01K67/027 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|