发明名称 |
USE OF HYALURONIC ACID DERIVATIVES FOR THE PREVENTION OF INFLAMMATORY ARTHRITIS |
摘要 |
Rheumatoid arthritis is a chronic inflammatory disease, leading to joint destruction. Conventional therapy is based on pain-reduction and an improvement in the frictional properties of joints, in order to delay the time for operative intervention. A lack of specifically-acting agents for drug-based therapy for arthritis exists. The formulations comprise sulphated hyaluronic acids with varying degrees of sulphation, or the pharmacologically acceptable salts thereof and, optionally, hyaluronic acid and/or hyaluronic acid uronide. The pharmaceutical formulations are highly concentrated injection preparations with an aqueous, viscous, gel-like, or paste-like form, or a low-concentration rinsing fluid for intra-articular application. |
申请公布号 |
WO0232407(A3) |
申请公布日期 |
2003.11.20 |
申请号 |
WO2001DE03984 |
申请日期 |
2001.10.19 |
申请人 |
HANS-KNOELL-INSTITUT FUER NATURSTOFF-FORSCHUNG E.V.;FRIEDRICH-SCHILLER-UNIVERSITAET JENA;VENBROCKS, RUDOLF;ROTH, ANDREAS;MUELLER, PETER-JUERGEN;MOELLER, STEPHANIE;OZEGOWSKI, JOERG;PESCHEL, GUNDELA |
发明人 |
VENBROCKS, RUDOLF;ROTH, ANDREAS;MUELLER, PETER-JUERGEN;MOELLER, STEPHANIE;OZEGOWSKI, JOERG;PESCHEL, GUNDELA |
分类号 |
A61K9/06;A61K9/08;A61K9/10;A61K31/728;A61K45/00;A61P19/02;A61P29/00 |
主分类号 |
A61K9/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|