| 发明名称 |
2-THIO-SUBSTITUTED IMIDAZOLE DERIVATIVES AND THE USE THEREOF IN THE PHARMACEUTICAL INDUSTRY |
| 摘要 |
The invention relates to 2-thio-substituted imidazole derivatives of the formula I in which the radicals R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3 </SUB>and R<SUB>4 </SUB>are as defined in the description. The compounds according to the invention have immunomodulating and/or cytokine-release-inhibiting action and are therefore suitable for treating disorders associated with a disturbed immune system. |
| 申请公布号 |
EP1362045(A2) |
申请公布日期 |
2003.11.19 |
| 申请号 |
EP20020716791 |
申请日期 |
2002.02.19 |
| 申请人 |
MERCKLE GMBH |
发明人 |
LAUFER, STEFAN;KOTSCHENREUTHER, DUNJA;MERCKLE, PHILIPP;TOLLMANN, KAROLA;STRIEGEL, HANS-GUENTER |
| 分类号 |
A61K31/164;A61K31/4439;A61K31/4545;A61K31/5377;A61P1/02;A61P1/04;A61P1/16;A61P1/18;A61P3/10;A61P9/00;A61P9/10;A61P11/00;A61P17/06;A61P17/14;A61P19/06;A61P19/10;A61P25/00;A61P25/08;A61P25/28;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P35/00;A61P37/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D401/04;C07D401/14;(IPC1-7):C07D401/04;A61K31/416 |
主分类号 |
A61K31/164 |
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