IMMORTALIZED HUMAN CELL LINES CONTAINING EXOGENOUS CYTOCHROME P450 GENES
摘要
<p>Non-tumorigenic, human bronchial epithelial cell lines are provided wherein the cell lines are capable of expressing cytochrome P450 genes which have been inserted into the cell lines. Also provided are methods and kits for identifying potential mutagens, cytotoxins, carcinogens, and chemotherapeutic agents utilizing these cell lines.</p>
申请公布号
EP0640137(B1)
申请公布日期
2003.11.19
申请号
EP19930912165
申请日期
1993.04.09
申请人
THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES;NESTEC S.A.
发明人
HARRIS, CURTIS, C.;GELBOIN, HARRY, V.;GONZALEZ, FRANK, J.;PFEIFER, ANDREA, M., A.
