AUTOLOGOUS BONE GRAFT MATERIAL

摘要

PROBLEM TO BE SOLVED: To provide a musculoskeletogenic (MSG) graft composite material prepared from a whole bone marrow aspirate (BMA) containing a native level of musculoskeletal progenitor cells (MSPCs).

SOLUTION: The composite material comprises (a) a prescribed suspension of a fractionated BMA comprising (i) the MSPCs present in a larger prescribed level than each native level in the whole BMA and (ii) red blood cells (RNCs) present in a lower prescribed level than each native level in the whole BMA and (b) a porous sterile matrix having at least 20 μm average pore size.

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