CYTOKINE GENE RECOMBINANT SILKWORM AND METHOD FOR PRODUCING THE PROTEIN

摘要

PROBLEM TO BE SOLVED: To easily obtain a recombinant cytokine using silkworm such as a high-purity feline interferon by producing an active cytokine in sericterium or cocoon silk.

SOLUTION: Gene recombinant silkworm is obtained by transferring a cytokine gene into silkworm chromosome using a gene recombinant vector comprising a gene sequence where a cytokine gene linked to a promoter functioning in the sericterium is linked to a sequence necessary for gene transfer into silkworm such as a transposon-derived sequence. The cytokine is extracted from the sericterium or cocoon of the above silkworm or offspring thereof and refined.

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