摘要 |
<p>Antitumor agents, tumor immunity inducers, T cell activators, and dendritic cell activators, highly safe and capable of inducing an antitumor immune reaction enabling immunotherapy for cancer in such a way that an antitumor effect is exerted on human distant tumors such as metastatic tumors. Methods for treating cancer using such agents, inducers and activators are also provided. A herpes simplex virus (inactivated HSV) or herpes simplex virus glycoprotein D (HSVgD) etc. is used as an effective ingredient of such antitumor agents, tumor immunity inducers, T cell activators, and dendritic cell activators. A specific example of the above-mentioned inactivation treatment is the combination of the ultraviolet irradiation treatment at 4 J/m<2> for 30 min using 254 nm ultraviolet light and heat treatment at 56 DEG C for 30 min.</p> |