4-AMINO-6,7-DIMETHOXY-2-(5-METHANSULFONAMIDO-1, , 3,4-TETRAHYDROISOCHINOL-2-YL)-5-(2- PYRIDYL)CHINAZOLINE MESYLAT UND POLYMORPHS

摘要

The present invention provides 4-amino-6,7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4-tetrahydroisoquinol-2-yl)-5-(2-pyridyl)quinazoline mesylate of the formulatogether with processes for preparing, and compositions containing it.The invention also relates to substantially pure anhydrous crystalline polymorphic forms of the free base.The compounds are particularly useful in the treatment of benign prostatic hyperplasia.