发明名称 |
APPARATUS FOR MEASURING CONCENTRATION OF ENDOTOXIN |
摘要 |
PROBLEM TO BE SOLVED: To provide an apparatus for measuring the concentration of endotoxin capable of incorporating part of a specimen liquid such as drugs from a storage tank, etc., for the specimen liquid by a pipe and continuously monitoring the concentration of endotoxin of a liquid of a low concentration of 50 EU/L or less in a short time. SOLUTION: The apparatus for measuring the concentration of the endotoxin comprises a means for incorporating the specimen liquid containing the endotoxin in a measuring circuit and sealing it; a means for circulating the sealed specimen liquid in the measuring circuit; a means for injecting a limulus reagent in the circulating specimen liquid and mixing both liquids; a particulate counting means for continuously measuring the concentration of particulates with the passage of time which occur in the mixed liquids introduced to a measuring cell; and a means for discharging the mixed liquids from the measuring circuit and cleaning the measuring circuit. By measuring the time required for a count value of the particulate counting means to reach a predetermined amount of change or the rate of change of the amount of change with the passage of time, the concentration of the endotoxin is computed in the apparatus for measuring the concentration of the endotoxin. COPYRIGHT: (C)2004,JPO
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申请公布号 |
JP2003322655(A) |
申请公布日期 |
2003.11.14 |
申请号 |
JP20020130811 |
申请日期 |
2002.05.02 |
申请人 |
DAICEN MEMBRANE SYSTEMS LTD;CENTRAL FILTER MFG CO LD |
发明人 |
ISHII KIYOSHI;HARADA TOKUZO;MIURA KAORU |
分类号 |
G01N33/579;G01N1/00;(IPC1-7):G01N33/579 |
主分类号 |
G01N33/579 |
代理机构 |
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