发明名称 |
Reprogramming cells for enhanced differentiation capacity using pluripotent stem cells |
摘要 |
Described in this disclosure is a new process whereby cells of one tissue type can be reprogrammed to produce cells of a different tissue type. Cells from a human donor are reprogrammed by culturing adjacent to primate pluripotent stem cells (in an undifferentiated or newly differentiated state) or in an environment supplemented by components taken from pPS cells. Simultaneously or in a subsequent step, the donor cells can be treated in a manner that enhances differentiation towards a different tissue type. In this manner, patients in need of tissue regeneration can be treated with cells differentiated and reprogrammed from their own autologous cell donation. |
申请公布号 |
US2003211603(A1) |
申请公布日期 |
2003.11.13 |
申请号 |
US20030344680 |
申请日期 |
2003.02.12 |
申请人 |
EARP DAVID J.;CARPENTER MELISSA K.;GOLD JOSEPH D.;LEBKOWSKI JANE S.;SCHIFF J. MICHAEL |
发明人 |
EARP DAVID J.;CARPENTER MELISSA K.;GOLD JOSEPH D.;LEBKOWSKI JANE S.;SCHIFF J. MICHAEL |
分类号 |
A61K35/12;C12N5/071;(IPC1-7):C12N5/08 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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