| 摘要 |
<p>The present invention provides a sensor device for detecting and quantifying a gene product in a cell or tissue section sample (101) by employing an analysis reagent that binds to the gene product to form a detectable product. The device comprises (a) a first and second coated plate (104), wherein the plates (104) are parallel to each other and are coated with a conductive material; (b) a first and second conductive plate (102), wherein the plates are juxtaposed over the coated plates (104); (c) a first and second conducting tape (103) connecting a first and second end of the coated plates (104) and the conductive plates (102), respectively; (d) a first and second gasket insulator (105) insulating a first and second end of the coated plates (104) and the conductive plates (102), respectively; (e) a voltage generator (109) connected to the first and second conductive plates (102) to apply an electric potential to the conductive plates (102); and (f) a detector (108). The first and second coated plates (104) provide a compartment for a cell or tissue section sample (101) and a conductive fluid. An analysis reagent is provided in the sample or tethered to a surface of the first or second coated plate (104) such that when the voltage generator (109) applies an electric potential to the conductive plates (102), the detector (108) will detect the interaction between charged materials within the cell or tissue section sample (101), migrating towards either surface of the coated plate (104), and the analysis reagent.</p> |
