| 发明名称 |
FUSIONS OF CYTOKINES AND TUMOR TARGETING PROTEINS |
| 摘要 |
A conjugate of a cytokine and a tumor targeting moiety (TTM) with the provisos that when cytokine is TNF-alpha, TNF-beta or IFN-gamma, the TTM is other than a CD13 ligant; when the cytokine is IL-12, the TTM is other than an antiboy to fibronectin; when the cytokine is TNF, the TTM is other than an antibody to the transferrin receptor; and when the cytokine is TNF, IFN-gamma or IL-2 the antibody is other than an antibody to the TAG72 antigen.
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| 申请公布号 |
WO03092737(A1) |
申请公布日期 |
2003.11.13 |
| 申请号 |
WO2003IB02515 |
申请日期 |
2003.04.30 |
| 申请人 |
MOLMED SPA;CORTI, ANGELO;CURNIS, FLAVIO |
发明人 |
CORTI, ANGELO;CURNIS, FLAVIO |
| 分类号 |
C12N15/09;A61K31/198;A61K31/704;A61K38/00;A61K38/17;A61K38/21;A61K45/00;A61K47/48;A61K48/00;A61K49/00;A61P35/00;C07K14/49;C07K14/52;C07K14/525;C07K14/54;C07K14/545;C07K14/55;C07K14/565;C07K14/57;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/02;(IPC1-7):A61K47/48;C07K14/705;C07K16/30 |
主分类号 |
C12N15/09 |
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