| 摘要 |
<p>SEQ ID Nos 1 and 2are the amino acid and nucleotide sequences of the deglycating enzyme of the invention. Variants, derivatives, homologues, analogs, fragments, salts and pharmaceutical compositions thereof are also provided that have direct or indirect deglycation activity. Deglycation occurring for example, by phosphorylation of molecules on glycoproteins or other sugar-bearing proteins. The Deglycating Enzymes of the invention are capable of degradation of low molecular weight amines, amino acids, sugar amines, glycoproteins and other sugar-bearing proteins. SEQ ID No 1, Deglycating Enzymes in general and antagonists thereof are considered in methods of providing therapy-especially for treatment of diabetes.</p> |
