发明名称 |
IMMORTALIZED HYPOTHALAMIC NEURONAL CELL LINES |
摘要 |
The present invention is directed to a method of preparing cell lines of hypothalamic origin. The method involves infecting fetal hypothalamic cells with a retroviral vector harbouring a viral oncogene, preferably SV-40 large T antigen, followed by selection and cloning. A plurality of cell lines have been prepared which express a variety of neuronal markers. The cell lines of the present invention are useful in the development of experimental models and in the treatment of disease. |
申请公布号 |
WO03093480(A2) |
申请公布日期 |
2003.11.13 |
申请号 |
WO2003CA00621 |
申请日期 |
2003.05.02 |
申请人 |
BELSHAM, DENISE;LOVEJOY, DAVID |
发明人 |
BELSHAM, DENISE;LOVEJOY, DAVID |
分类号 |
A61K38/17;C07K14/705 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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