POLYMETALLIC MOLECULAR COMPLEXES USED AS CONTRAST AGENTS IN MAGNETIC IMAGE RESONANCE

摘要

According to the invention, a novel type of contrast agent having a superparamagnetic behaviour at ambient temperature is synthesised for use as a contrast agent in magnetic image resonance. The invention relates to the use of a polymetallic molecular complex as a contrast agent which has a superparamagnetic behaviour at ambient temperature and which reduces the longitudinal relaxation time (T1). At ambient temperature, said type of compounds behaves in a similar manner to a paramagnet, i.e. the resulting magnetisation fluctuates with time at a characteristic frequency that depends on temperature. In the case of superparamagnetic compounds, the resulting magnetic moment is greater than for paramagnetic compounds and, as a result, superparamagnetic compounds reduce the relaxation time of the hydrogen nuclei of water molecules more effectively.