摘要 |
<p>An industrially advantageous process for the preparation of 2-aminopyrazine derivatives represented by the general formula [I] or acid addition salts thereof: [I] [wherein R1 is hydrogen, alkyl having 1 to 6 carbon atoms, or aryl; R2 is hydrogen, alkyl having 1 to 6 carbon atoms, aryl, or halogeno; and R3 is hydrogen, alkyl having 1 to 6 carbon atoms, aryl, or aralkyl], characterized by using a reaction accelerator for the formation of pyrazine ring which contains an iron compound as the active ingredient.</p> |