发明名称 |
METHODS AND COMPOSITIONS FOR USE IN PREPARING SIRNAS |
摘要 |
Methods and compositions for producing siRNAs, e.g., in the form of a d-siRNA composition, from dsRNAs are provided. In the subject methods, a dsRNA is contacted with a composition that includes an activity that cleaves dsRNA into siRNAs, where the composition efficiently cleaves dsRNA into siRNAs. siRNAs produced by the subject methods find use in a variety of applications, particularly in applications where the specific reduction or silencing of a gene is desired. Also provided are kits for use in practicing the subject invention. |
申请公布号 |
WO03093430(A2) |
申请公布日期 |
2003.11.13 |
申请号 |
WO2003US13671 |
申请日期 |
2003.04.30 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;MYERS, JASON;FERRELL, JAMES |
发明人 |
MYERS, JASON;FERRELL, JAMES |
分类号 |
C12N9/22;C12N15/11;C12N15/113 |
主分类号 |
C12N9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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