| 发明名称 |
Method for treating cartilage disorders |
| 摘要 |
The present invention relates to a method for the treatment of a cartilage disorder, including cartilage damaged by injury or degenerative cartilagenous disorders. The method involves contacting the cartilage with an IGF-1 analog with altered affinity for IGF-binding proteins (IGFBPs) or an IGFBP displacer peptide that prevents the interaction of an IGF with an IGFBP and does not bind to a human IGF receptor.
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| 申请公布号 |
US2003211992(A1) |
申请公布日期 |
2003.11.13 |
| 申请号 |
US20020271869 |
申请日期 |
2002.10.16 |
| 申请人 |
GENENTECH, INC. |
发明人 |
CHEN YVONNE MAN-YEE;CLARK ROSS G.;COCHRAN ANDREA G.;DUBAQUIE YVES;FIELDER PAUL J.;FILVAROFF ELLEN;LOWMAN HENRY B.;MORTENSEN DEBORAH L.;ROBINSON IAIN C.A.F.;SKELTON NICHOLAS J. |
| 分类号 |
A61K38/00;A61K38/17;A61K38/30;C07K7/08;C07K14/47;C07K14/65;(IPC1-7):A61K38/18 |
主分类号 |
A61K38/00 |
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