Peptides and methods for the control of obesity

摘要

Disclosed is a peptide derivative having the formula:X<1>-Z-Q-arg-trp-NH2Wherein: X<1 >is an acyl group, Z is amino-2-naphthyl-carboxylic acid or histidine, Q is (D)phenylalanine or p-iodo-(D)phenylalanine, or a pharmacologically acceptable salt, complex or derivative thereof, the peptide derivative having melanocortin-4 receptor agonist activity.