发明名称 EPOTHILONE DERIVATIVE FOR THE TREATMENT OF HEPATOMA AND OTHER CANCER DISEASES
摘要 The present invention relates to a method of treating a warm-blooded animal, especially a human, having a cancer disease selected from hepatoma; primary fallopian tube cancer; primary peritoneal cancer; breast cancer progressing after treatment with hormonal agents or radiotherapy; renal cell carcinoma progressing after treatment with a cytokine, radiotherapy and/or nephrectomy ,; melanoma progressing after radiotherapy; prostate cancer progressing after orchiectomy, ovarian cancer progressing after treatment with a platinum compound or radiotherapy; and colorectal cancer progressing after radiothera py and/or treatment with oxaliplatin or irinotecan; and metastasis thereof comprising administering to said animal a therapeutically effective amount o f an epothilone derivative of formula (I).
申请公布号 CA2483826(A1) 申请公布日期 2003.11.13
申请号 CA20032483826 申请日期 2003.04.30
申请人 NOVARTIS AG 发明人 ROTHERMEL, JOHN DAVID
分类号 C07D277/24;A61K31/425;A61K31/426;A61K31/427;A61K41/00;A61K45/06;A61P35/00;A61P35/04;(IPC1-7):A61K31/425 主分类号 C07D277/24
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