| 摘要 |
In a process for purifying an enzymatic preparation of L-asparaginase obtained from an L-asparaginase-producing micro-organism belonging to the genus Serratia wherein said micro-organism produces, together with the L-asparaginase, factors which inactivate the enzymatic activity of L-asparaginase, the improvement which comprises inhibiting the L-asparaginase inactivating factors and thus stabilizing the L-asparaginase preparation during the purification process by adding to said enzymatic preparation a heavy metal ion such as silver, cadmium, copper or zinc, and recovering purified L-asparaginase having an effective anti-tumor activity.
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