| 摘要 |
The present invention provides a novel approach to vaccination and/or treatment using encapsulated cells for eliciting immune responses. More specifically, the present invention is to provide a method or process for inducing an immune response in a host, wherein the process comprises the ste ps of: enclosing genetically engineered antigen-producing cells comprising one or more transgene, into an immunoisolating implantable device to provide encapsulated antigen-producing cells; introducing the encapsulated antigen- producing cells in the host; production of the transgene antigen product; bi - directional passage of the produced antigen product through the pores of the microcapsules, with preclusion of the passage of the antigen-producing cells therethrough; delivery of a continuous infusion of antigen to the host; activation of the immune system in response to the antigen.
|
