发明名称 |
Synergistic methods and formulations for tumor therapy |
摘要 |
<p>The present invention provides a synergistic method for the treatment of cancer which comprises administering to a mammalian specie in need thereof a synergistically, therapeutically effective amount of: (1) at least agent selected from the group consisting of cytotoxic agents and cytostatic agents, and (2) a compound of formula Ior a pharmaceutically acceptable salt thereof. The present invention further provides a pharmaceutical composition for the synergistic treatment of cancer which comprises at least one agent selected from the group consisting of antiproliferative cytotoxic agents and antiproliferative cytostatic agents, a compound of formula I, and a pharmaceutically acceptable carrier.</p> |
申请公布号 |
CZ20023220(A3) |
申请公布日期 |
2003.11.12 |
申请号 |
CZ20020003220 |
申请日期 |
2001.03.22 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
LEE FRANCIS Y. |
分类号 |
C07D239/94;A61K31/138;A61K31/275;A61K31/337;A61K31/395;A61K31/427;A61K31/454;A61K31/4725;A61K31/513;A61K31/517;A61K31/55;A61K31/5513;A61K31/555;A61K31/695;A61K31/7068;A61K39/395;A61K41/00;A61K45/00;A61P35/00;A61P35/04;A61P43/00;C07D401/14;C07D403/06;C07D409/12;C07D409/14;C07D417/12;(IPC1-7):A61K31/551;C07D243/06 |
主分类号 |
C07D239/94 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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