发明名称 MUSCARINIC AGONISTS
摘要 Substituted 1,4,5,6-tetrahydropyrimidine compositions, substituted 1,2,3,6-tetrahydropyrimidine compositions and substituted 3,4,5,6-tetrahydropyridine compositions of the formulae (see formulae I, II, III) where A, R and Z, are various functional groups, are disclosed. They are useful for stimulating muscarinic receptors including, for example, treating the symptoms of cognitive disorders, especially impaired memory, which are associated with decreased acetylcholine synthesis and cholinergic cell degeneration.
申请公布号 CA2113424(C) 申请公布日期 2003.11.11
申请号 CA19922113424 申请日期 1992.08.12
申请人 THE UNIVERSITY OF TOLEDO 发明人 DUNBAR, PHILIP G.;MESSER, WILLIAM S., JR.;DURANT, GRAHAM J.;HOSS, WAYNE P.
分类号 A61K31/445;A61K31/44;A61K31/443;A61K31/505;A61K31/506;A61P25/02;A61P25/04;A61P25/14;A61P25/18;A61P25/28;A61P27/06;A61P43/00;C07D211/72;C07D211/78;C07D239/06;C07D239/14;C07D239/16;C07D405/04;C07D411/04;C07D413/04;C07D417/04;(IPC1-7):C07D239/06 主分类号 A61K31/445
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