| 摘要 |
PROBLEM TO BE SOLVED: To provide an oral composition with potent antitussive action and a method to improve antitussive action. SOLUTION: The oral composition contains at least one of compounds of formula (1): HOOC-CH(NH<SB>2</SB>)CH<SB>2</SB>CH<SB>2</SB>CONH-R (1), (wherein R is H atom or an optionally substituted alkyl group) including 2-amino-4-(N-ethylcarbamoyl) butanoic acid and 2-amino-4-[N-(2-sulfoethyl) carbamoyl] butanoic acid or their pharmaceutically acceptable salts, a central antitussive and a bronchodilator, if necessary. COPYRIGHT: (C)2004,JPO
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