| 发明名称 |
Composition containing anti-MIF antibody |
| 摘要 |
The present invention relates to compositions and methods for inhibiting the release and/or biological activity of migration inhibitory factor (MIF). In particular, the invention relates to the uses of such compositions and methods for the treatment of various conditions involving cytokine-mediated toxicity, which include, but are not limited to shock, inflammation, graft versus host disease, and/or autoimmune diseases.
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| 申请公布号 |
US6645493(B1) |
申请公布日期 |
2003.11.11 |
| 申请号 |
US19950471705 |
申请日期 |
1995.06.06 |
| 申请人 |
THE PICOWER INSTITUTE FOR MEDICAL RESEARCH |
发明人 |
BUCALA RICHARD J.;MITCHELL ROBERT A.;BERNHAGEN JURGEN;CALANDRA THIERRY F.;CERAMI ANTHONY |
| 分类号 |
A61K39/395;A61K48/00;A61P43/00;C07K14/52;C07K14/575;C07K14/72;C07K16/24;C07K16/26;C12N15/113;C12N15/85;(IPC1-7):A61K39/00;C07K16/00;C12P21/00 |
主分类号 |
A61K39/395 |
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