| 发明名称 |
METHOD FOR PRODUCING PHENYLALANINE DERIVATIVE AND SYNTHETIC INTERMEDIATE THEREOF |
| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To produce a new phenylalanine derivative having excellent inhibitory effects onα<SB>4</SB>integrin-mediated cell adhesion or a pharmaceutically acceptable salt thereof. <P>SOLUTION: The method for producing the phenylalanine derivative represented by formula (I) [wherein Q is CH<SB>2</SB>or the like; Y is a lower alkyl or CO<SB>2</SB>; R is a protected carboxyl group] comprises condensing a compound represented by formula (IV) with a compound represented by formula (III) (X<SP>1</SP>and X<SP>2</SP>are each a halogen atom) and then eliminating a protective group. <P>COPYRIGHT: (C)2004,JPO</p> |
| 申请公布号 |
JP2003321429(A) |
申请公布日期 |
2003.11.11 |
| 申请号 |
JP20030050173 |
申请日期 |
2003.02.27 |
| 申请人 |
TANABE SEIYAKU CO LTD |
发明人 |
INOUE ISAO;KURODA TORU;YOSHIOKA RYUZO |
| 分类号 |
C07C231/12;C07B61/00;C07C227/16;C07C229/36;C07C233/87;C07F5/02;(IPC1-7):C07C231/12 |
主分类号 |
C07C231/12 |
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