| 发明名称 |
Synthesis of glycoconjugates of the lewis Y epitope and uses thereof |
| 摘要 |
The present invention provides a method of synthesizing an allyl pentasaccharide having the structure:as well as related oligosaccharide ceramides and other glycoconjugates useful as vaccines for inducing antibodies to epithelial cancer cells in an adjuvant therapy therefor, and in a method for preventing recurrence of epithelial cancer.
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| 申请公布号 |
US6645935(B2) |
申请公布日期 |
2003.11.11 |
| 申请号 |
US20010977185 |
申请日期 |
2001.10.12 |
| 申请人 |
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH;THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY NEW YORK |
发明人 |
DANISHEFSKY SAMUEL J.;BEHAR VICTOR;LLOYD KENNETH O. |
| 分类号 |
A61K31/00;A61K31/70;A61K31/7028;A61K35/16;A61K38/00;A61K39/00;A61K39/39;A61P35/00;C07H3/06;C07H15/10;C07H15/18;C07H17/02;C07K1/04;C07K9/00;C07K16/30;C07K16/44;(IPC1-7):A61K38/16;C07H17/00 |
主分类号 |
A61K31/00 |
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