发明名称 Vitamin D analogues
摘要 Compounds of the formula Iwherein X represents hydrogen or hydroxy; R<1 >and R<2>, which may be the same or different, represent hydrogen, (C1-C4)alkyl optionally substituted with one hydroxyl group or one or more fluorine atoms, or, together with the carbon atom to which they are attached, R<1 >and R<2 >form a (C3-C5)carbocyclic ring; R<3 >represents (C1-C4)alkyl, (C1-C4)alkoxy or a halogen atom, such as fluorine, chlorine, bromine, or iodine, and in-vivo hydrolyzable esters thereof with pharmaceutically acceptable acids, may be used in the prophylaxis and/or treatment of dieases characterized by abnormal cell differentiation and/or cell proliferation.
申请公布号 US6646143(B2) 申请公布日期 2003.11.11
申请号 US20010787664 申请日期 2001.03.20
申请人 LEO PHARMACEUTICAL PRODUCTS LTD. A/S 发明人 HANSEN KAI HOLST
分类号 A61K31/59;A61P3/10;A61P9/12;A61P13/12;A61P17/00;A61P17/06;A61P17/10;A61P17/14;A61P19/00;A61P19/08;A61P19/10;A61P25/28;A61P31/18;A61P35/00;A61P35/02;A61P37/02;A61P37/06;C07C401/00;(IPC1-7):A61K31/593;A61K31/592;C07C463/00 主分类号 A61K31/59
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