| 摘要 |
A process for preparing beta -santalol, useful in perfume compositions, from 3-methylnorcamphor comprising the steps of 1. ALKYLATING 3-METHYLNORCAMPHOR WITH beta -BROMOPROPIONALDEHYDE ETHYLENE GLYCOL ACETAL; 2. REACTING THE REACTION PRODUCT OF Step (1) with a methylmetallic compound, such as methyllithium, followed by acid hydrolysis; 3. REACTING THE REACTION PRODUCT OF Step (2) with (carbethoxyethylidene)triphenylphosphorane; 4. DEHYDRATING THE REACTION PRODUCT OF Step (3) with a dehydrating agent, such as thionyl chloride; and 5. REDUCING THE REACTION PRODUCT OF Step (4) with a reducing agent, such as lithium aluminum hydride, to obtain beta -santalol, AND NOVEL COMPOUNDS PRODUCED THEREIN ARE DISCLOSED.
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