| 摘要 |
<p>Diketohydrazine derivatives represented by the following general formula (I) (wherein each symbol is as defined in the description) and pharmaceutically acceptable salts thereof: (I) Because of having a cysteine protease inhibitory activity, the compounds represented by the general formula (I) are useful as remedies for inflammatory diseases, immune diseases, ischemic diseases, respiratory diseases, circulatory diseases, blood diseases, nerve diseases, liver/biliary duct diseases, bone/joint diseases, metabolic diseases and so on. Because of having an elastase inhibitory activity, these compounds are also useful as remedies for COPD (chronic obstructive pulmonary disease) and so on.</p> |
