A method of continuously manufacturing lactam under high temperature and high pressure fluid, characterized by comprising the step of leading ketone and a hydroxylamine compound in a reaction field under high temperature and high pressure conditions of circulating fluid to efficiently synthesize lactam in a short time, whereby lactam can be rapidly synthesized continuously from ketone under the high temperature and high pressure fluid conditions of 175<°>C or higher in temperature range and 7 MPa or higher in pressure range.
申请公布号
WO03091208(A1)
申请公布日期
2003.11.06
申请号
WO2002JP04425
申请日期
2002.05.07
申请人
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE;HATAKEDA, KIYOTAKA;SATO, OSAMU;IKUSHIMA, YUTAKA;TORII, KAZUO