发明名称 Chemical compounds
摘要 The invention relates to compounds of the formula (I): wherein: ring C is 9 or 10-membered bicyclic heteroaromatic group containing at least one nitrogen atom in the ring attached to Z and optionally containing a further 1-3 heteroatoms, selected independently from O, S, and N, with the proviso that ring C is not a quinazoline, quinoline or cinnoline group; either any one of G1, G2, G3, G4 and G5 is nitrogen and the other four are -CH-; or G1, G2, G3, G4 and G5 are all -CH-; Z is -O-, NH-, -S-, CH2- or a direct substituents R<1 >may be attached at any free carbon atom of the indole, azaindole or indazole group; m is an integer from 0 to 2; R<b >represents hydrogen or another value as defined herein; R<1 >represents hydrogen, hydroxy, halogeno, C1-4alkyl, or any other value as defined herein; R<2 >represents hydrogen, hydroxy, halogeno, cyano, nitro, trifluoromethyl, C1-3alkyl, C1-3alkoxy, C1-3alkylsulphanyl, -NR<3>R<4 >(wherein R<3 >and R<4>, which may be the same or different, each represents hydrogen or C1-3alkyl), or R<5>X<1>- (wherein R<5 >and X<1 >are as defined herein) and salts thereof, processes for the preparation of such compounds, pharmaceutical compositions
申请公布号 US2003207878(A1) 申请公布日期 2003.11.06
申请号 US20030343236 申请日期 2003.01.30
申请人 HENNEQUIN LAWRENT FRANCOIS ANDRE 发明人 HENNEQUIN LAWRENT FRANCOIS ANDRE
分类号 A61K31/50;A61K31/502;A61K31/5025;A61K31/519;A61P3/10;A61P9/10;A61P15/08;A61P17/00;A61P17/06;A61P27/02;A61P29/00;A61P35/00;A61P43/00;C07D401/14;C07D495/04;(IPC1-7):A61K31/541;A61K31/537;A61K31/53;A61K31/496;C07D417/14;C07D413/14;C0743/14 主分类号 A61K31/50
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