| 摘要 |
The invention relates to a cardiopulmonary bypass pump that can be used with medication to put the heart into asystole or near asystolic status. This gives the physician enough time to perform diagnostic and/or therapeutic procedures and also allows the diseased heart to recover from ischemic insults without additional hemodynamic stress, and also facilitates certain cardiac procedures. The patent describes equipment used in conjunction with medication to temporarily replace the function of the heart and to allow the heart to survive with minimal oxygen supply for hours or days, and for the heart to recover from ischemic or other insult or other damage without being subjected to a heavy working load. The invention provides a means to stop blood flow to the heart for a relatively long period of time, thereby allowing the performance of certain procedures that require coronary artery blockade. It also allows the heart to stop contracting, which may result in safer and easier performance of some procedures. A pump is used to drain blood from the patient's veins into a gas exchanger. The exchanger oxygenates the blood and removes carbon dioxide from the blood, then the pump pumps the blood back into the patient. The device maintains blood pressure at a preset level in a pulsatile fashion. A medication is given to the patient while the device is in use in order to stop the heart or slow the heart rate to a minimal level to decrease cardiac oxygen requirements without significant hemostasis in the pulmonary circulation. The systemic circulation can be supported entirely by the pump with the heart in asystole. This allows enough time for certain diagnostic and therapeutic procedures to be performed. The device may also allow the diseased heart to recover from an ischemic insult. The system receives feedback from arterial pressure sensors and utilizes this data to maintain the arterial pressure at a preset level by adjusting the pump activity. There is an electrocardiogram (EKG) gating mechanism that coordinates the pump activity with contraction of the heart to avoid active contraction of the heart against the pulsatile pressure head of the device pump. There is an interaction between pressure control and EKG gating to ensure that the arterial pressure is maintained at a preset level and to avoid the heart contracting against the pump.
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