| 摘要 |
The present invention provides substituted pyrazine derivatives of Formula (I), that are CRF1 receptor antagonists, including human CRF1 receptors. This invention also relates to use of compounds of the invention for treating a disorder or condition, the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as CNS disorders, particularly anxiety-related disorders and mood disorders.
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| 申请人 |
PHARMACIA & UPJOHN COMPANY;CORBETT, JEFFREY, W.;ENNIS, MICHAEL, D.;FRANK, KRISTINE, E.;FU, JIAN-MIN;HOFFMAN, ROBERT, L.;VERHOEST, PATRICK, R. |
发明人 |
CORBETT, JEFFREY, W.;ENNIS, MICHAEL, D.;FRANK, KRISTINE, E.;FU, JIAN-MIN;HOFFMAN, ROBERT, L.;VERHOEST, PATRICK, R. |
