摘要 |
The specification discloses an alginate composition in which medicaments or cells may be interspersed with aqueous insoluble alginate molecules, so that pellets prepared by this procedure would survive the stomach contents, any enzymatic activity contained therein, as well as the low pH, and gradually dissolve in the intestinal tract behaving as a controlled release system of any specific medicament or cells including, but not limited to, vaccines that are entrapped in the alginate coacervate. Orally administered particles so prepared could be used to eliminate the need for parenteral needle inoculation of various medicaments in man and animals. |