MOLECULAR MIMETICS OF MENINGOCOCCAL B EPITOPES WHICH ELICIT FUNCTIONALLY ACTIVE ANTIBODIES

摘要

Molecular mimetics of a surface-exposed epitope on loop 4 of PorA of Neisseria meningitidis serogroup B (MenB) P1.2 serosubtype and antibodies produced against the same are disclosed. Compositions containing such molecular mimetics or the antibodies thereto can be used to prevent MenB disease, as well as for diagnosis of MenB infection.