POLYMER COMPOSITIONS CONTAINING A MACROCYLIC TRIENE COMPOUND

摘要

A polymer composition for use in delivering a macrocyclic triene compound to a subject is described. The polymer composition is comprised of a polymer substrate containing as the macrocyclic triene compound a 40-0-hydroxy alkyl rapamycin derivative, where the alkyl group contains between 7-11 carbon atoms. The composition is useful for treating any condition responsive to rapamycin or everolimus, and methods of treatment using the polymer composition are described.