PATHOLOGICAL TISSUE DETECTION AND TREATMENT EMPLOYING TARGETED BENZOINDOLE OPTICAL AGENTS
摘要
Novel tumor specific phototherapeutic and photodiagnostic agents are disclosed. The compounds consist of a carbocyanine dye for visualization, photosensitizer for photodynamic treatment, and tumor receptor-avid peptide for site-specific delivery of the probe and phototoxic agent to diseased tissues. A combination of these elements takes full advantage of the unique and efficient properties of each component for an effective patient care management.
申请公布号
WO03032901(A3)
申请公布日期
2003.11.06
申请号
WO2002US32021
申请日期
2002.10.07
申请人
MALLINCKRODT INC.;ACHILEFU, SAMUEL, I.;RAJAGOPALAN, RAGHAVAN;BUGAJ, JOSEPH, E.;DORSHOW, RICHARD, B.
发明人
ACHILEFU, SAMUEL, I.;RAJAGOPALAN, RAGHAVAN;BUGAJ, JOSEPH, E.;DORSHOW, RICHARD, B.