CHITOSAN UND INFLUENZA-ANTIGEN(E) ENTHALTENDE IMPFSTOFF-ZUBEREITUNGEN ZUR VERABREICHUNG DURCH EINE MUKOSA

摘要

A vaccine composition adapted for mucosal administration is provided. The composition includes one or more influenza vaccine antigens and an effective adjuvant amount of an acid addition salt of a chitosan wherein the chitosan is a deacetylated chitin which is at least 80% deacetylated and has a weight average molecular weight of between 10,000 and 100,000.