Pyridyl ethers and thioethers as ligands for nicotinic acetylcholine receptor and its therapeutic application

摘要

The present invention provides compounds of the formula: wherein m is 0, 1 or 2; p is 0 or 1; Y is O, S, S(O) or S(O)2 and R<1 >to R<7 >are various substituents as selective modulators of the nicotinic acetylcholine receptor useful in the treatment of pain, Alzheimer's disease, memory loss or dementia or loss of motor function.