| 摘要 |
<p>This inventions discloses and claims 3-substituted amino-1H-indole-2-carboxylic acid and 3-substituted amino-benzothiophene-2-carboxylic acid derivatives for use in treating allergy, asthma, rhinitis, dermatitis, B-cell lymphomas, tumors and diseases associated with bacterial, rhinovirus or respiratory syncytial virus (RSV) infections. It has now been found that the compounds of this invention are capable of modulating T helper (Th) cells, Th1/Th2, and thereby capable of inhibiting the transcription of interieukin-4(IL-4) message, IL-4 release or IL-4 production.</p> |
