发明名称 Methods of treatment with selective EP4 receptor agonists
摘要 The present invention provides a method of treating hypertension, liver failure, loss of patency of ductus arteriosus, glaucoma or ocular hypertension in a patient, comprising administering to the patient a therapeutically effective amount of a selective EP4 receptor agonist of Formula I or a prodrug thereof, a pharmaceutically acceptable salt of the selective EP4 receptor agonist or prodrug or a stereoisomer or diastereomeric mixture of the EP4 receptor agonist, prodrug or salt, wherein the variables X, Z, Q, <custom-character file="US20030207925A1-20031106-P00900.TIF" wi="20" he="20" id="custom-character-00001"/>, and R<2 >are as defined in the specification.
申请公布号 US2003207925(A1) 申请公布日期 2003.11.06
申请号 US20030386307 申请日期 2003.03.11
申请人 CAMERON KIMBERLY O.;LEFKER BRUCE A.;KNIGHT DELVIN R. 发明人 CAMERON KIMBERLY O.;LEFKER BRUCE A.;KNIGHT DELVIN R.
分类号 C07D403/10;A61K31/4015;A61K31/4025;A61K31/427;A61K31/559;A61P1/16;A61P9/10;A61P9/12;A61P27/06;A61P43/00;C07D207/26;C07D207/27;C07D403/06;C07D403/12;C07D405/06;C07D409/06;C07D409/12;C07D409/14;C07D417/06;C07D417/12;C07D417/14;(IPC1-7):A61K31/427;A61K31/402;A61K31/401 主分类号 C07D403/10
代理机构 代理人
主权项
地址