| 摘要 |
Provided is a method for screening for effective agents for the treatment of cancer which method comprises testing a putative agent that is likely to disrupt a critical normal gene product present in said cancer for its cytotoxic and/or growth inhibitory effect upon a cancer cell sample, and identifying an effective agents as an agent which is cytotoxic to, and/or inhibiting to the growth of the cancer cell sample. This invention further provides an agent capable of disrupting a critical normal gene in such a manner as to be cytotoxic to, or inhibiting to the growth of a cancer cell, and a method of treating a cancer patient with such an agent.
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